ANTISENSE OLIGONUCLEOTIDES FOR TREATING UNWANTED PIGMENTATION OF THE SKIN AND HAIR

摘要

The invention relates to an oligonucleotide or a physiologically compatible salt thereof, that is able to hybridise with an mRNA or a gene sequence encoding at least one structure contributing to the pigmentation of the skin and/or hair, said structures contributing to (I) the actual melanin synthesis (melanosome structures) and/or to (II) the expression of said melanosome structures and/or to (III) the transfer of the melanosomes (into the keratinocytes).