发明名称 |
NITROGENOUS FUSED HETEROAROMATIC RING DERIVATIVE |
摘要 |
<p>A compound represented by the formula (I): [wherein A1 represents hydrogen, etc.; j and k each is 0 or 1; ... (P)j = represents a double bond, etc.; ... (Q)k = represents a double bond, etc.; and one of W1 and W2 represents E-O-W, etc. and the other represents hydrogen, etc., provided that E represents a divalent group formed by removing two hydrogen atoms from a benzene ring, etc. and W represents a group represented by the formula (II-1)] or a pharmaceutically acceptable salt of the compound. The compound and salt have antagonistic activity against a histamine H3 receptor or inverse agonistic activity against a histamine H3 receptor and are useful in the prevention or treatment of metabolic diseases, circulatory diseases, or nervous diseases.</p> |
申请公布号 |
WO2005077953(A1) |
申请公布日期 |
2005.08.25 |
申请号 |
WO2005JP02948 |
申请日期 |
2005.02.17 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD.;TAKAHASHI, TOSHIYUKI;KANATANI, AKIO;TOKITA, SHIGERU;YOSHIMOTO, RYO |
发明人 |
TAKAHASHI, TOSHIYUKI;KANATANI, AKIO;TOKITA, SHIGERU;YOSHIMOTO, RYO |
分类号 |
C07D487/04;(IPC1-7):C07D487/04;A61P25/14;A61P25/08;A61P25/02;A61P25/00;A61P19/06;A61P13/12;A61P9/12;A61P9/10;A61P9/04;A61P9/00;A61P5/00;A61P3/10;A61P3/06;A61P3/04;A61P3/00;A61P1/16;A61K31/53;A61K31/502;C07D487/14;A61P25/16;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P43/00;A61P39/02;A61P27/00 |
主分类号 |
C07D487/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|