发明名称 |
DIHYDROTETRABENAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
摘要 |
<p>The invention provides novel isomers of dihydrotetrabenazine, individual enantiomers and mixtures thereof wherein the dihydrotetrabenazine is a 3,11 b-cis- dihydrotetrabenazine. Also provided are methods for the preparation of the novel isomers, pharmaceutical compositions containing them and their use in treating hyperkinetic movement disorders such as Huntington's disease, hemiballismus, senile chorea, tic, tardive dyskinesia and Tourette's syndrome.</p> |
申请公布号 |
WO2005077946(A1) |
申请公布日期 |
2005.08.25 |
申请号 |
WO2005GB00464 |
申请日期 |
2005.02.11 |
申请人 |
CAMBRIDGE LABORATORIES LIMITED;TRIDGETT, ROBERT;CLARKE, IAN;TURTLE, ROBERT;JOHNSTON, GRANT |
发明人 |
CLARKE, IAN;TURTLE, ROBERT;JOHNSTON, GRANT |
分类号 |
A61P25/14;A61P25/24;C07D455/06;C07D471/04;C07D491/14;(IPC1-7):C07D455/06;A61K31/473 |
主分类号 |
A61P25/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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