发明名称 HUMAN MONOCHRONAL ANTIBODY TO EPIDERMAL CELL GROWTH FACTOR RECEPTOR
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a human monochronal antibody for treating solid cancers with an antibody to a human epidermal cell growth factor receptor (EGF-r) by an antibody treatment. <P>SOLUTION: A perfect human monochronal antibody to the human epidermal cell growth factor receptor (EGF-r) is provided. An amino acid sequence containing a nucleotide sequence to encode heavy chain and light chain immunoglobulin molecules, specially, sequences corresponding to contiguous heavy chain and light chain sequences from CDR1 to CDR3 are provided. And also, a hybridoma revealing the immunoglobulin molecules and the monochronal antibody like this are provided. <P>COPYRIGHT: (C)2005,JPO&NCIPI</p>
申请公布号 JP2005225884(A) 申请公布日期 2005.08.25
申请号 JP20050050969 申请日期 2005.02.25
申请人 ABGENIX INC 发明人 JAKOBOVITS AYA;YANG XIAO-DONG;GALLO MICHAEL;JIA XIAO-CHI
分类号 C12N15/02;A61K38/00;A61K39/395;A61P35/00;C07K16/28;C12N15/09;C12P21/08;(IPC1-7):C07K16/28 主分类号 C12N15/02
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