INFECTIOUS BRONCHITIS VIRUS WITH AN ALTERED SPIKE GENE
摘要
<p>The present invention provides a vaccine for use in the protection of poultry against infectious bronchitis comprising an attenuated infectious bronchitis virus (IBV) and a pharmaceutical acceptable carrier or diluent, characterized in that the attenuated IBV comprises a heterologous spike gene. Such a vaccine is based on IBV strain Beaudette that is able to express a spike gone derived from a different IBV strain. The vaccines provided by the present invention also allow the administration via the in ovo route.</p>
申请公布号
WO2004078203(A9)
申请公布日期
2005.08.25
申请号
WO2004EP50247
申请日期
2004.03.03
申请人
AKZO NOBEL N.V.;INSTITUTE FOR ANIMAL HEALTH;CAVANAGH, DAVID;BRITTON, PAUL;TARPEY, IAN