| 摘要 |
The present invention is directed to the process for the preparation of 2'-deoxy-2'-halo-beta-L-arabinofuranosyl nucleosides, and in particular, 2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl thymine (L-FMAU), from L-arabinose, which is commercially available and less expensive than L-ribose or L-xylose, in ten steps. All of the reagents and starting materials are inexpensive and no special equipment is required to carry out the reactions.
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