STEROIDS FOR CANCER TREATMENT

摘要

The present invention relates to novel compounds which are 7alpha-substituted 17-alkylene-16alpha-hydroxy steroidal estrogens. This invention specifically relates to estrogen derivatives which contain 7alpha-substituents and which exhibit anti-estrogenic properties. The present invention also relates to use of said compounds as a medicament, and for the treatment of estrogen dependent disorders, a pharmaceutical composition comprising one or more of said compounds and a method of treatment.