摘要 |
[Subject] To provide regulatory T cells that suppress activated CD8 + killer T cells with tissue-damaging or cytotoxic effects. [Solution means] CD8 + CD122 + T cell subsets are provided as regulatory T cells that suppress activity of activated CD8 + killer T cells. Administration of these T cell subsets can suppress tissue/cell damages. In addition, it has become possible to explore agents that augment immunosuppressive activity of these T cell subsets by using the experimental method described in the present invention. |