发明名称 HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS
摘要 Compounds of formula (I) are antagonists of VLA-4 and/or alpha 4 beta 7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
申请公布号 EP1001764(A4) 申请公布日期 2005.08.24
申请号 EP19980926122 申请日期 1998.05.29
申请人 MERCK & CO., INC. (A NEW JERSEY CORP.) 发明人 DURETTE, PHILIPPE, L.;HAGMANN, WILLIAM, K.;MACCOSS, MALCOLM;MILLS, SANDER, G.;MUMFORD, RICHARD, A.;VAN RIPER, GAIL, M.;SCHMIDT, JACK, A.;KEVIN, NANCY, J.
分类号 A61K38/00;A61K31/401;A61K31/445;A61P1/04;A61P9/10;A61P11/06;A61P25/00;A61P37/08;A61P43/00;C07K5/06;C07K5/078;(IPC1-7):C07F9/02;A61K31/405;A61K31/395;A61K31/41;A61K31/415;A61K31/425;A61K31/435 主分类号 A61K38/00
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