发明名称 |
Method for measuring Endotoxin |
摘要 |
<p>The presence of endotoxin in the outer membrane of cell wall of a Gram-negative bacteria is used to determine bacterial contamination in a biological product. The amount of endotoxin present in a biological product is accurately measured without infuluence of a limulus reaction-activating substance which causes a false-positive reaction, by a method including the steps of: inactivating the limulus reaction-activating substance, if any, in the biological product, by exposing the biological product to a surfactant at a temperature ranging from the surfactant's freezing point to 50 DEG C; and measuring the amount of endotoxin present in the biological product, using a limulus reagent.</p> |
申请公布号 |
EP0837330(B1) |
申请公布日期 |
2005.08.24 |
申请号 |
EP19970118261 |
申请日期 |
1997.10.21 |
申请人 |
SEIKAGAKU CORPORATION |
发明人 |
TAMURA, HIROSHI;TANAKA, SHIGENORI;WATANABE, MAKI |
分类号 |
G01N33/579;(IPC1-7):G01N33/579 |
主分类号 |
G01N33/579 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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