发明名称 Peptides which stimulate the expression of the cytokines of inflammation and promote tissue regeneration
摘要 A pharmaceutical composition for stimulating production of cytokines of inflammation including a peptide corresponding to formula (I) below: <?in-line-formulae description="In-line Formulae" end="lead"?>(A)<SUB>n</SUB>-A1-A1-A2-A1-A3-A4-A1-(A)<SUB>m</SUB><?in-line-formulae description="In-line Formulae" end="tail"?> in which A is any amino acid, n and m are each whole numbers from 0 to 20 whose sum n+m is between 0 and 20, A1 is a basic amino acid and more particularly lysine (Lys) or arginine (Arg), A2 is an amino acid selected from the group consisting of basic amino acids, glutamic acid (Glu), glycine (Gly) and aspartic acid (Asp), A3 is an amino acid selected from the group consisting of basic amino acids, proline (Pro), glutamic acid (Glu) and glutamine (Gln), A4 is an amino acid selected from the group consisting of basic amino acids, glutamic acid (Glu), glycine (Gly), serine (Ser) and valine (Val), and a pharmaceutically acceptable carrier.
申请公布号 US6932973(B2) 申请公布日期 2005.08.23
申请号 US20020116391 申请日期 2002.04.04
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS 发明人 BARRITAULT DENIS;ACHOUR AMMAR;COURTY JOSE
分类号 A61K38/00;A61P9/00;A61P9/10;A61P17/00;A61P17/02;A61P21/00;A61P31/18;A61P37/00;A61P37/04;A61P43/00;C07K7/00;C07K14/16;C07K14/47;C07K14/475;C07K14/515;C07K14/52;(IPC1-7):A61K45/00 主分类号 A61K38/00
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