发明名称 Purified forms of DNase
摘要 The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
申请公布号 US6932965(B2) 申请公布日期 2005.08.23
申请号 US20020155407 申请日期 2002.05.22
申请人 GENENTECH, INC. 发明人 FRENZ JOHN;SHIRE STEVEN J.;SLIWKOWSKI MARY B.
分类号 C12N15/09;A61K35/74;A61K38/00;A61K38/45;A61K38/46;A61P11/00;C07K1/00;C07K1/18;C07K1/22;C07K4/12;C07K14/47;C12N9/16;C12N9/22;(IPC1-7):C12N9/22 主分类号 C12N15/09
代理机构 代理人
主权项
地址