发明名称 |
Pyranosyl cytosines: pharmaceutical formulations and methods |
摘要 |
This invention is directed to novel pyranosyl cytosine compounds depicted graphically as structure I. This invention is further directed to a unique methodology for their preparation using solid-phase methodology. These hexopyranosyl cytosine derived natural product analogs share their parent compounds broad-spectrum antimicrobial and anti-fungal profile and represent a vast, novel compound class of 50S rRNA directed inhibitors of protein translation.
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申请公布号 |
US6933288(B2) |
申请公布日期 |
2005.08.23 |
申请号 |
US20020067017 |
申请日期 |
2002.02.04 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MIGAWA MICHAEL T.;SWAYZE ERIC E.;GRIFFEY RICHARD H. |
分类号 |
A61K31/506;A61K31/519;A61K38/00;C07D405/04;C07H19/06;C07K5/02;(IPC1-7):C07D407/04;A61K31/706 |
主分类号 |
A61K31/506 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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