发明名称 Antisense modulation of microsomal triglyceride transfer protein expression
摘要 Antisense compounds, compositions and methods are provided for modulating the expression of microsomal triglyceride transfer protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding microsomal triglyceride transfer protein. Methods of using these compounds for modulation of microsomal triglyceride transfer protein expression and for treatment of diseases associated with expression of microsomal triglyceride transfer protein are provided.
申请公布号 US2005181376(A1) 申请公布日期 2005.08.18
申请号 US20040759618 申请日期 2004.01.16
申请人 ISIS PHARMACEUTICALS, INC. 发明人 CROOKE ROSANNE M.;GRAHAM MARK J.
分类号 A61K38/00;C12N15/113;(IPC1-7):A61K48/00;C12Q1/68;C07H21/02 主分类号 A61K38/00
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