发明名称 |
Dipeptide inhibitors of beta-secretase |
摘要 |
Dipeptide derived inhibitors of the beta-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Abeta peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Abeta peptide formation and in pharmaceutical compositions.
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申请公布号 |
US2005182138(A1) |
申请公布日期 |
2005.08.18 |
申请号 |
US20050075232 |
申请日期 |
2005.03.08 |
申请人 |
ELAN PHARMACEUTICALS, INC. |
发明人 |
JOHN VARGHESE;TUNG JAY;HOM ROY;GUINN ASHLEY;FANG LAWRENCE;GAILUNAS ANDREA;MAMO SHUMEYE S. |
分类号 |
C07K5/02;C07K5/103;(IPC1-7):A61K31/165;C07C237/40 |
主分类号 |
C07K5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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