发明名称 |
TAXANE CHEMOSENSITIVITY PREDICTION TEST |
摘要 |
The present invention provides a method for determining the chemosensitivity of a cancer cell to a taxane comprising assessing the effect of the taxane on the expression level or activity of one or more cell cylce molecules in a cancer cell. Such a method makes use of an automated analyzer system wherein cell cycle paramteres (molecules) such as CDKI kinase activity, CDK1 expression, CDK2 kinase activity, CDK2 expression, MAD2 expression, Cyclin Bl, Cyclin E expression, p2l expression, and CDK6 expression; are assessed. The present invention further provides a method of obtaining a cell cycle profile of a cancer cell that is sensitive to a taxane.
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申请公布号 |
WO2005020794(A8) |
申请公布日期 |
2005.08.18 |
申请号 |
WO2004US27661 |
申请日期 |
2004.08.25 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;SYSMEX CORPORATION;UENO, NAOTO, T.;ISHIHARA, HIDEKI;SUDO, TAMOTSU;MATSUSHIMA, TOMOKO |
发明人 |
UENO, NAOTO, T.;ISHIHARA, HIDEKI;SUDO, TAMOTSU;MATSUSHIMA, TOMOKO |
分类号 |
A61B;B05D5/00;C07H21/02;C07H21/04;C08K5/00;C12Q1/48;C12Q1/68;G01N33/50;(IPC1-7):A61B/ |
主分类号 |
A61B |
代理机构 |
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