摘要 |
A compound represented by the following general formula (I) or a salt thereo f. [Chemical formula 1] (I) (In the formula, R1, R2, and R3 each independently represents hydrogen or C1-3 alkyl, provided that at least one of R1, R2, and R3 is not hydrogen; R4 represents substituted amino; and R5 represents optionally substituted carboxy.) Also provided is a peptidyl arginine deiminase type IV inhibitor. With this inhibitor, diseases in which a peptid yl arginine deiminase participates (e.g., articular rheumatism and multiple sclerosis) can be prevented and/or treated.
|