| 发明名称 |
HADHs as modifiers of the p21 pathway and methods of use |
| 摘要 |
Human HADH genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of HADH are provided.
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| 申请公布号 |
US2005181481(A1) |
申请公布日期 |
2005.08.18 |
| 申请号 |
US20050103035 |
申请日期 |
2005.04.11 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
FRIEDMAN LORI;PLOWMAN GREGORY D.;FUNKE ROEL P.;BELVIN MARCIA;LI DANXI;ROBERTSON STEPHANIE A. |
| 分类号 |
G01N33/50;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/574;G01N33/68;(IPC1-7):C12P21/02;C07H21/04;C07K14/705 |
主分类号 |
G01N33/50 |
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