Piperdine derivatives useful as CCR3 antagonists

摘要

The use of CCR3 antagonists of the formula I or a pharmaceutically acceptable salt thereof for the treatment of asthma is disclosed, as well as novel compounds of the formula II, pharmaceutical compositions comprising them, and their use in the treatment of asthma, wherein R, R^a, X, X^a, R¹, R², R^2a, R¹⁴, R^14a, R¹⁶ and n are as defined in the specification.