发明名称 |
Use of alkaline phosphatase for the detoxification of LPS present at mucosal barriers |
摘要 |
The present invention provides a use for alkaline phosphatase for the manufacture of a medicament for the prevention or reduction of toxic LPS influx through a mucosal lining of a mammalian body cavity. A source of alkaline phosphatase is administered for the prophylaxis or treatment of LPS mediated or exacerbated diseases. The invention also provides compositions comprising a source of alkaline phosphatase for the prevention or reduction of (toxic) LPS influx or passage through mucosal layers. |
申请公布号 |
AU2005210581(A1) |
申请公布日期 |
2005.08.18 |
申请号 |
AU20050210581 |
申请日期 |
2005.02.04 |
申请人 |
PHARMAAWARE SEPSIS B.V. |
发明人 |
RUDI BRANDS;KLAAS POELSTRA |
分类号 |
A61K38/46;A23C9/12;A23L1/03 |
主分类号 |
A61K38/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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