摘要 |
<P>PROBLEM TO BE SOLVED: To obtain a benzo[de]quinoline derivative having a new structure, a medicine effective for cancer therapy, a medicine and a food each for preventing or treating osteopathy caused mainly by bone embrittlement, each using the compound as active ingredient. <P>SOLUTION: The benzo[de]quinoline derivative is represented by formula(1)[ wherein, R<SP>1</SP>is H, a lower alkyl or alkenyl; R<SP>2</SP>is H or a (substituted) alkyl, alkenyl or aryl; R<SP>3</SP>is a nonsubstituted unshared electron pair, H, an alkyl, alkenyl or aryl, forming an immonium cation with positive electric charge ]. A second version of the derivative is represented by formula(2). The medicines and foods each containing either one of the above derivatives as active ingredient are also provided, respectively. <P>COPYRIGHT: (C)2005,JPO&NCIPI |