发明名称 PEPTIDYL ARGININE DEIMINASE TYPE IV INHIBITOR
摘要 <p>A compound represented by the following general formula (I) or a salt thereof. [Chemical formula 1] (I) (In the formula, R&lt;1&gt;, R&lt;2&gt;, and R&lt;3&gt; each independently represents hydrogen or C1-3 alkyl, provided that at least one of R&lt;1&gt;, R&lt;2&gt;, and R&lt;3&gt; is not hydrogen; R&lt;4&gt; represents substituted amino; and R&lt;5&gt; represents optionally substituted carboxy.) Also provided is a peptidyl arginine deiminase type IV inhibitor. With this inhibitor, diseases in which a peptidyl arginine deiminase participates (e.g., articular rheumatism and multiple sclerosis) can be prevented and/or treated.</p>
申请公布号 WO2005075414(A1) 申请公布日期 2005.08.18
申请号 WO2005JP01574 申请日期 2005.02.03
申请人 YOKOHAMA CITY UNIVERSITY;SATO, MAMORU;SHIMIZU, TOSHIYUKI;HASHIMOTO, HIROSHI;YAMADA, MICHIYUKI;HIDAKA, YUJI 发明人 SATO, MAMORU;SHIMIZU, TOSHIYUKI;HASHIMOTO, HIROSHI;YAMADA, MICHIYUKI;HIDAKA, YUJI
分类号 A61K38/00;A61K31/198;A61K45/00;A61P19/02;A61P29/00;A61P43/00;C07C279/14;(IPC1-7):C07C279/14 主分类号 A61K38/00
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