DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN CHOLECYSTOKININ RECEPTOR B (CCKBR)

摘要

The invention provides a human CCKBR which is associated with the cardiovascular diseases, dermatological diseases, gastroenterological diseases, cancer, inflammation, hematological diseases, respiratory diseases, neurological diseases, urological diseases and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, dermatological diseases, gastroenterological diseases, cancer, inflammation, hematological diseases, respiratory diseases, neurological diseases, urological diseases and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of CCKBR as well as pharmaceutical compositions comprising such compounds.