发明名称 |
RECOMBINANT FACTOR VIII HAVING INCREASED SPECIFIC ACTIVITY |
摘要 |
The present invention relates to recombinant factor VIII having a specific activity that is higher than that of the corresponding wild-type factor VIII. The present invention also relates to methods of making and using the recombinant factor VIII. The present invention also relates to an isolated nucleic acid molecule that encodes the recombinant factor VIII, as well as DNA expression systems and host cells containing the isolated nucleic acid molecule. |
申请公布号 |
WO2005055930(A3) |
申请公布日期 |
2005.08.18 |
申请号 |
WO2004US40234 |
申请日期 |
2004.12.02 |
申请人 |
UNIVERSITY OF ROCHESTER;FAY, PHILIP, J.;WAKABAYASHI, HIRONAO |
发明人 |
FAY, PHILIP, J.;WAKABAYASHI, HIRONAO |
分类号 |
A61K;A61K35/14;A61K35/16;A61K38/00;C07K1/00;C07K14/00;C07K14/755;C12N15/63;C12N15/85 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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