发明名称 |
DIAZABICYCLIC ARYL DERIVATIVES AS CHOLINERGIC RECEPTOR MODULATORS |
摘要 |
This invention relates to novel diazabicyclic aryl derivatives which are fou nd to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervo us system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro- degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemicals substanc es.
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申请公布号 |
CA2554050(A1) |
申请公布日期 |
2005.08.18 |
申请号 |
CA20052554050 |
申请日期 |
2005.02.01 |
申请人 |
NEUROSEARCH A/S |
发明人 |
OLSEN, GUNNAR M.;PETERS, DAN;NIELSEN, ELSEBET OSTERGAARD;JORGENSEN, TINO DYHRING;TIMMERMANN, DANIEL B. |
分类号 |
A61K31/551;A61P25/16;A61P25/28;C07D471/08 |
主分类号 |
A61K31/551 |
代理机构 |
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