发明名称 |
Method for the determination of endothelins for medical diagnostic, antibodies and kits |
摘要 |
The in vitro test to determine the formation of endolithins in human whole blood or plasma or serum identifies the development of endolethin-1 and big-endolethin-1. C-terminal fragments of preproendolethin-1 are determined which are recognized by antibodies which bond to peptides. The peptide sequences match the amino acid ranges of 93-212 of the preproendolethin-1. The determination in a biological fluid is by a competitive or sandwich immunoassay, working with at least one marked antibody specific only to a particular peptide fragment.
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申请公布号 |
EP1564558(A1) |
申请公布日期 |
2005.08.17 |
申请号 |
EP20040003295 |
申请日期 |
2004.02.13 |
申请人 |
B.R.A.H.M.S AKTIENGESELLSCHAFT |
发明人 |
BERGMANN, ANDREAS, DR.;STRUCK, JOACHIM, DR. |
分类号 |
G01N33/574;G01N33/68;G01N33/74;(IPC1-7):G01N33/74 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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