发明名称 Use of vasopeptidase inhibitors in the treatment of metabolic diseases, nephropathy and advanced glycation end-product associated diseases
摘要 The invention describes and claims the use of vasopeptidase inhibitors of formula (I) for the treatment of nephropathy in diabetic or non-diabetic patients, including diabetic or non-diabetic nephropathy, glomerulonephritis, glomerular sclerosis, nephrotic syndome, hypertensive nephrosclerosis, microalbuminuria or end stage renal disease, or insulin resistance or of metabolic diseases associated with advanced glycation end-products, such as diabetic complications, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, myocardial infarction and/or diabetic cardiomyopathy, or atherosclerosis or endothelial dysfunction.
申请公布号 US6930103(B2) 申请公布日期 2005.08.16
申请号 US20030607521 申请日期 2003.06.26
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH 发明人 SCHAEFER STEFAN;LINZ WOLFGANG;BLEICH MARKUS;HUBER JOCHEN
分类号 A61K31/55;(IPC1-7):A61K31/55 主分类号 A61K31/55
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