摘要 |
A melanin-concentrating hormone antagonist comprising a compound of the formula (I): wherein Ar<SUP>1 </SUP>is a cyclic group which may be substituted; X and Y are the same or different and are a spacer having a main chain of 1 to 6 atoms; Ar is a condensed polycyclic aromatic ring which may be substituted; R<SUP>1 </SUP>and R<SUP>2 </SUP>are the same or different and are hydrogen atom or a hydrocarbon group which may be substituted; or R<SUP>1 </SUP>and R<SUP>2</SUP>, together with the adjacent nitrogen atom, may form a nitrogen-containing heterocyclic ring which may be substituted; or R<SUP>2</SUP>, together with the adjacent nitrogen atom and Y, may form a nitrogen-containing heterocyclic ring which may be substituted; or R<SUP>2</SUP>, together with the adjacent nitrogen atom, Y and Ar, may form a condensed ring; or a salt thereof is useful as an agent for preventing or treating obesity, etc.
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