发明名称 |
Substituted alkylaminopyridazinone derivatives, process for the preparation thereof and pharmaceutical composition containing the same |
摘要 |
The invention relates to substituted alkylaminopyridazinone derivatives of the general Formula (I), (wherein R<SUB>1 </SUB>is hydrogen or alkyl having 1-4 carbon atoms; one of X and Y stands for hydrogen or halogen and the other represents a group of the general Formula (II), R<SUB>2 </SUB>is hydrogen or alkyl having 1-4 carbon atoms; n is 1, 2 or 3; R<SUB>3 </SUB>stands for hydrogen, alkyl having 1-4 carbon atoms or aryl-(C<SUB>1-4 </SUB>alkyl); Z stands for oxygen; or R<SUB>3 </SUB>and Z together with the groups placed between them form a piperazine ring; and R<SUB>4 </SUB>stands for hydrogen, halogen, trifluoromethyl or alkoxy having 1-4 carbon atoms) and pharmaceutically acceptable acid addition salts thereof. The invention compounds are useful in the treatment of anxiolytic conditions and cognitive disorders.
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申请公布号 |
US6930110(B2) |
申请公布日期 |
2005.08.16 |
申请号 |
US20040491151 |
申请日期 |
2004.06.28 |
申请人 |
EGIS GYOGYSZERGYAR RT. |
发明人 |
BARKOCZY JOZSEF;EGYED ANDRAS;GACSALYI ISTVAN;HARSING LASZLO;KOMPAGNE HAJNALKA;NAGY PETER KOTAY;LEVAY GYOERGY;LEVELEKI CSILLA;MARKO BERNADETT MARTONNE;KOVACS ANIKO MIKLOSNE;SCHMIDT EVA;SIMIG GYULA;SZENASI GABOR;WELLMANN JANOS |
分类号 |
A61K31/50;A61K31/501;A61P25/14;A61P25/22;A61P25/28;C07B61/00;C07D237/22;C07D401/12;C07D403/12;C07D405/12;(IPC1-7):A61K31/501;C07D405/14 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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