LO-CD2A ANTIBODY AND USES THEREOF FOR INHIBITING T-CELL ACTIVATION AND PROLIFERATION

摘要

The present invention relates to an LO-CD2a antibody and methods of using su ch antibodies or molecules that bind to a portion of the same epitope (or a portion thereof) to prevent and inhibit an immune respons e in human patients, preferably, where the immune response is mediated by the activation and proliferation of T-cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.