发明名称 Stable hydrate of a muscarinic receptor antagonist
摘要 A stable solid hydrate of a muscarinic receptor antagonist is useful in the treatment of irritable bowel syndrome, diverticular disease, oesophageal achalasia, chronic obstructive airways disease, over active bladder (including symptoms of incontinence, urge and frequency), urinary incontinence, neurogenic urinary urgency or pollakiuria, treatment of bladder functional disorder, urinary leakage, painful or difficult urination caused by neurogenic bladder, spastic or hypertonic bladder, dysfunctional bladder syndrome, gastrointestinal disorders including gastrointestinal hyperactivity, and relaxing effect on intestinal smooth muscle cells.
申请公布号 US6930188(B2) 申请公布日期 2005.08.16
申请号 US20030396887 申请日期 2003.03.25
申请人 NOVARTIS INTERNATIONAL PHARMACEUTICAL, LTD. 发明人 DUNN PETER JAMES;MATTHEWS JOHN GEORGE;NEWBURY TREVOR JACK;O'CONNOR GARRY
分类号 A61K31/40;A61P1/04;A61P11/00;A61P13/00;A61P13/02;A61P21/02;A61P43/00;C07D405/06;(IPC1-7):C07D307/78 主分类号 A61K31/40
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