摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical preparations with the highly flexible and deformable coating, capable of transporting drugs into the body of warm blood creatures. SOLUTION: Combinations of at least three amphipatic substances forming aggregate suspensions in a polar liquid are used. Judicious choice of system components, which differ at least 2-times to 10-times in solubility, ensures said aggregates to have extended, unusually adaptable surfaces. At least two of said three system components are soluble substances, and at least one of which is an active ingredient and preferably a drug. The third component, alternatively, can take the role of a drug. Furthermore, an appropriate method is demonstrated for manufacture and utilization of a carrier. The application also describes new formulations of nonsteroidal anti-inflammatory drugs (NSAIDs) based on the complex aggregates. COPYRIGHT: (C)2005,JPO&NCIPI
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