摘要 |
PROBLEM TO BE SOLVED: To provide (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione having improved bioavailability, etc., or its pharmacologically permissible salt and its crystal. SOLUTION: The invention provides hydrate of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione expressed by formula (I) or its pharmacologically permissible salt, and hydrate crystal of (E)-8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione expressed by formula (I) or its pharmacologically permissible salt, etc. COPYRIGHT: (C)2005,JPO&NCIPI
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