发明名称 Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
摘要 A conjugate of a toxin and a cytokine, and a fusion protein comprising a bispecific antibody that has a first specificity for a cell marker specific to a malignant cell and a second specificity for a region of IL-15alpha, each optionally further comprising a radionuclide, are useful therapeutic reagents for treating leukemias and lymphomas.
申请公布号 US2005175582(A1) 申请公布日期 2005.08.11
申请号 US20050056187 申请日期 2005.02.14
申请人 IMMUNOMEDICS, INC. 发明人 GOLDENBERG DAVID M.
分类号 C12N15/09;A61K38/00;A61K39/395;A61K47/48;A61K51/00;A61K51/08;A61P35/00;A61P35/02;C07K14/54;C07K14/715;C07K16/28;C07K16/46;C07K19/00;(IPC1-7):A61K51/00;A61K38/19;C07K14/52 主分类号 C12N15/09
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