| 摘要 |
A quinolone antibacterial which has potent antibacterial activity against gram-positive bacteria and gram-negative bacteria and is highly safe. Also provided are a compound represented by the following formula (1): (wherein R<1> is hydrogen, alkyl, cycloalkyl, or substituted carbonyl derived from an amino acid, dipeptide, or tripeptide; R<2> is hydrogen, alkyl, or cycloalkyl; R<3> is hydrogen, amino, halogeno, or alkyl; R<4> is hydrogen, phenyl, acetoxymethyl, pivaloyloxymethyl, ethoxycarbonyl, choline, dimethylaminoethyl, 5-indanyl, phthalizinyl, 5-alkyl-2-oxo-1,3-dioxol-4-ylmethyl, 3-acetoxy-2-oxobutyl, alkyl, alkoxymethyl, or phenylalkyl; and X, X<1>, and X<2> each is hydrogen or halogeno), a salt thereof, and a hydrate of either. The antibacterial contains any of these. Furthermore provided is a therapeutic agent for infectious diseases which contains any of the compound, salt, and hydrate. |
