| 摘要 |
The invention relates to a method for the production of particles labelled with the radioactive isotope Rhenium-188 (Re-188) and a kit for carrying out said method. Such radioactively-charged particles can be used in medicine, preferably in oncology and nuclear medicine, for the radiotherapy of tumours , or metastases of tumours. According to the method, the particles are suspend ed in a solution and heated, whereupon the solution firstly has a pH value of p H 1 to pH 3 and contains a tin-II salt and a Re-188 perrhenate salt. After 45 to 70 minutes of heating the pH value is increased. The suspension obtained aft er increasing the pH may be directly used for radiotherapy in patients. Radiati on protection of the personnel is significantly improved as a result of the unnecessary washing step, along with a corresponding saving in time. Furthermore, the requirement of tin-II salt for the labelling is reduced and the labelling yield is increased.
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