COMPOSITIONS AND METHODS WITH ENHANCED THERAPEUTIC ACTIVITY
摘要
Novel quinone and catechol compositions, compositions containing prodrugs of quinone and catechol compositions, and methods of use for the treatment of solid tumor cancers and other vascular proliferative disorders. The disclosure particularly relates to the discovery of dual activity agents capable of generating both a vascular targeting effect and direct tumor cell cytotoxicity in order to achieve an enhanced anti-tumor response in a patient.
申请公布号
WO2004078126(A3)
申请公布日期
2005.08.11
申请号
WO2004US06175
申请日期
2004.03.01
申请人
OXIGENE, INC.;CHAPLIN, DAVID, J.;EDVARDSEN, KLAUS;PINNEY, KEVIN, G.;PREZIOSO, JOSEPH, ANTHONY;WOOD, MARK
发明人
CHAPLIN, DAVID, J.;EDVARDSEN, KLAUS;PINNEY, KEVIN, G.;PREZIOSO, JOSEPH, ANTHONY;WOOD, MARK