| 发明名称 |
Modified CEA and uses thereof |
| 摘要 |
The invention discloses immunogenic CEA agonist polypeptides/proteins comprising a modified epitope containing the amino acid sequence YLSGADLNL, nucleic acids coding therefor, vectors and/or cells comprising said nucleic acids, and mixtures and/or compositions thereof. Methods for eliciting or inducing CEA-specific immune responses utilizing the aforementioned agents are also disclosed.
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| 申请公布号 |
EP1561817(A2) |
申请公布日期 |
2005.08.10 |
| 申请号 |
EP20050004454 |
申请日期 |
2001.07.27 |
| 申请人 |
AVENTIS PASTEUR LIMITED;THERION BIOLOGICS;NATIONAL CANCER INSTITUTE |
发明人 |
BERINSTEIN, NEIL;TARTAGLIA, JAMES;TINE, JOHN A.;PANICALI, DENNIS L.;GRITZ, LINDA;SCHLOM, JEFFREY |
| 分类号 |
C12N15/09;A61K35/74;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K48/00;A61P35/00;A61P43/00;C07K14/47;C07K14/705;C07K14/82;C12N5/10;C12N7/01;C12N15/12;(IPC1-7):C12N15/12;C12N15/86 |
主分类号 |
C12N15/09 |
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