CELL GROWTH REGULATOR

摘要

The present inventors examined cell growth of human colon cancer cell lines and breast cancer cell lines using L-2-phenylglycine, which is considered to be an amino acid transporter ATB<0,+> inhibitor, as a test substance to reveal a concentration-dependent cell growth inhibitory effect. This result shows that inhibition of ATB<0,+> activity may suppress cell growth. Suppression of the amino acid transporter ATB<0,+> activity may be an important index in developing growth inhibitors for cancer cells and such.