发明名称 NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
摘要 Compound of formula (I): wherein: R<SUB>1</SUB>, R<SUB>2</SUB>, R<SUB>3</SUB>, R<SUB>4</SUB>, R<SUB>6</SUB>, R<SUB>8</SUB>, R<SUB>9 </SUB>and R<SUB>10</SUB>, which may be the same or different, each represent a group selected from hydrogen, hydroxy, alkoxy, alkyl, arylalkoxy, alkoxycarbonylalkoxy and OR' wherein R' represents an ionised or ionisable group, R<SUB>5 </SUB>represents a group selected from alkyl, aryl and heteroaryl, R<SUB>7 </SUB>represents a group selected from hydrogen, hydroxy, alkoxy, alkyl and cycloalkyl, or R<SUB>7 </SUB>represents a nitrogen-containing or oxygen-containing heterocycle, its optical isomers, hydrates and solvates thereof and addition salts thereof, with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful as anti-cancer agents.
申请公布号 PL372984(A1) 申请公布日期 2005.08.08
申请号 PL20030372984 申请日期 2003.06.18
申请人 LES LABORATOIRES SERVIER 发明人 BRION JEAN-DANIEL;ISRAEL LUCIEN;LE RIDANT ALAIN;HARPEY CATHERINE;RABHI CHERIF;KALOUN EL BACHIR
分类号 A61K31/4709;A61P35/00;A61P43/00;C07D405/04;C07D405/14 主分类号 A61K31/4709
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