发明名称 |
Method of modulating tissue growth using Frzb Protein |
摘要 |
An isolated cDNA encoding a growth-inducing protein, Frzb, capable of stimulating bone, cartilage, muscle, and nerve tissue formation. Frzb binds to and modulates the activity of Wnt growth factors which play a role in various developmental and neoplastic processes. The cDNA and protein sequences of human, bovine and Xenopus Frzb are provided. Production and purification of recombinant Frzb are also described.
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申请公布号 |
US6924367(B2) |
申请公布日期 |
2005.08.02 |
申请号 |
US20010028051 |
申请日期 |
2001.12.19 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
LUYTEN FRANK P.;MOOS, JR. MALCOLM;HOANG BANG;WANG SHOUWEN |
分类号 |
A61K38/00;A61K38/17;A61K48/00;C07H21/04;C07K14/705;C07K14/71;C12N15/09;C12N15/12;C12P21/06;(IPC1-7):C07H21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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地址 |
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