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发明名称
对掌性丙酸衍生物之制备方法
摘要
本发明有关一种用于制备式I化合物之新颖方法，093129276-p01.bmp其包含在包含钌与对掌性二膦配位基或包含铑与对掌性二膦配位基之催化剂存在下所进行之式(II)化合物的催化不对称氢化作用，093129276-p02.bmp其中R^1、R^2、R^3及R^4系如说明书及申请专利范围所定义。式I化合物及其相应的盐及／或酯系医药活性物质。093129276-p01.bmp
申请公布号
TW200524919
申请公布日期
2005.08.01
申请号
TW093129276
申请日期
2004.09.27
申请人
赫孚孟拉罗股份公司
发明人
克特 普恩坦纳;米开朗基罗 史卡隆
分类号
C07D413/12;C07D333/54;A61K31/422
主分类号
C07D413/12
代理机构
代理人
陈长文
主权项
地址
瑞士
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