发明名称 Piperidinderivater som neurokinin-1-antagonister
摘要 The invention relates to compounds of the formulawherein R<1 >is optionally substituted phenyl, morpholinyl, piperazinyl, pyrrolidinyl, piperidinyl or is thiomorpholinyl, 1-oxo-thiomorpholinyl or 1,1-dioxothiomorpholinyl. These compounds have a good affinity to the NK-1 receptor and they are therefore suitable in the control or treatment of diseases, related to this receptor.
申请公布号 DK1360184(T3) 申请公布日期 2005.08.01
申请号 DK20020710043T 申请日期 2002.01.28
申请人 F. HOFFMANN-LA ROCHE AG 发明人 KOLCZEWSKI, SABINE;ROEVER, STEPHAN;SCHNIDER, PATRICK
分类号 A61K31/4545;A61P29/00;C07D211/14;C07D295/12;C07D401/04;(IPC1-7):C07D401/04;A61K31/454 主分类号 A61K31/4545
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