发明名称 Nf-kb inhibitors
摘要 The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-beta phosphorylation of IkappaB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-kappaB in which diseases excessive activation of NF-kappaB is implicated.
申请公布号 US2005165087(A1) 申请公布日期 2005.07.28
申请号 US20040516836 申请日期 2004.12.03
申请人 CALLAHAN JAMES F.;LI YUE HU 发明人 CALLAHAN JAMES F.;LI YUE HU
分类号 A61K31/381;A61P1/04;A61P3/10;A61P7/00;A61P9/10;A61P11/06;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07D333/36;C07D333/38;C07D333/40;(IPC1-7):A61K31/381 主分类号 A61K31/381
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