| 发明名称 |
Nf-kb inhibitors |
| 摘要 |
The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-beta phosphorylation of IkappaB. In so doing these aminothiophene inhibitors block pathological activation of transcription factor NF-kappaB in which diseases excessive activation of NF-kappaB is implicated.
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| 申请公布号 |
US2005165086(A1) |
申请公布日期 |
2005.07.28 |
| 申请号 |
US20040510841 |
申请日期 |
2004.10.08 |
| 申请人 |
CALLAHAN JAMES F.;LI YUE H. |
发明人 |
CALLAHAN JAMES F.;LI YUE H. |
| 分类号 |
C07D333/50;A61K31/381;A61P1/00;A61P3/10;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/04;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/12;A61P31/18;A61P35/00;A61P37/02;A61P43/00;C07D333/74;C07D333/78;(IPC1-7):A61K31/381;C07D333/76 |
主分类号 |
C07D333/50 |
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