发明名称 |
Multiplexed capillary electrophoresis systems |
摘要 |
Multi-capillary systems for high-throughput electrophoretic separation and detection of biomolecules are disclosed. One embodiment of the invention uses galactomannans as a size-sieving matrix for multi-channel electrophoretic separations of biomolecules. Multi-color detection for the simultaneous analysis of controls and standards in the same channels as the samples, and endogenous fluorescence detection are also disclosed. Another embodiment of the invention is a two dimensional system for separation of complex samples, using multiplexed capillary electrophoresis system as the second dimension, with a fraction collection step connecting the two separation steps. The systems allow for separations to be accomplished with a highly parallel manner, or in a two-dimensional format.
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申请公布号 |
US2005161329(A1) |
申请公布日期 |
2005.07.28 |
申请号 |
US20050511282 |
申请日期 |
2005.04.08 |
申请人 |
HUTTERER KATARIINA M.;OLSON NELS A.;JOVANOVICH STEVAN B.;ARMSTRONG THOMAS M.;BURGI DEAN;DOLNIK VLADISLAV |
发明人 |
HUTTERER KATARIINA M.;OLSON NELS A.;JOVANOVICH STEVAN B.;ARMSTRONG THOMAS M.;BURGI DEAN;DOLNIK VLADISLAV |
分类号 |
G01N21/64;G01N27/447;G01N27/453;G01N30/46;G02B21/00;(IPC1-7):G01N27/453 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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