发明名称 |
METHOD FOR NGF ASSAY FOR IN VITRO DIAGNOSIS OF BREAST CANCER AND THERAPEUTIC USE |
摘要 |
<p>In vitro diagnosis of breast cancer comprises detecting nerve growth factor (NGF) in a patient sample. ACTIVITY : Cytostatic. MECHANISM OF ACTION : Inhibition of NGF. MCF-7 breast cancer cells were grown to 40% confluence then incubated in presence of K-252a, a known inhibitor of NGF. After an unspecified time, the number of tumor cells was measured; it was about 0.36 million (per 35 mm disk) in absence of inhibitor but only 0.27 and 0.21 million at inhibitor concentrations 5 and 10 nM, respectively.</p> |
申请公布号 |
EP1556699(A2) |
申请公布日期 |
2005.07.27 |
申请号 |
EP20030778473 |
申请日期 |
2003.10.28 |
申请人 |
BIOMERIEUX;UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE |
发明人 |
ADRIAENSSENS, ERIC;CHOQUET-KASTYLEVSKY, GENEVIEVE;DOLLE, LAURENT;EL-YAZIDI, BELKOURA, IKRAM;HONDERMARCK, HUBERT |
分类号 |
G01N33/574;(IPC1-7):G01N33/574 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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地址 |
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