APPLYING ANTAGONIST OF CENTRAL CANNABINOID RECEPTOR FOR PREPARING DRUGS DESIGNATED FOR RELIEF IN SMOKING CEASING

摘要

FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention proposes applying N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazol-3-carboxamide or its salt for manufacturing a medicinal agent used for treatment of nicotine dependence and/or symptoms of nicotine withdrawal syndrome and a method for help in ceasing using tobacco. The claimed compound is known as antagonist of central cannabinoid receptors and agent used for treatment of disorders associated with using psychoactive substances. Indicated compounds are effective with respect to complete or partial tobacco abstinence with elimination of attenuation of nicotine withdrawal syndrome and patients show reduced weight loss or its absence. ^ EFFECT: valuable medicinal properties of antagonist. ^ 3 cl, 5 ex