发明名称 AGENT FOR PREVENTING OR TREATING NEUROPATHY.
摘要 <p>The present invention provides an agent for preventing or treating neuropathy having superior action and low toxicity. This agent comprises a compound represented by the formula:wherein ring A is a 5-membered aromatic heterocycle containing 2 or more nitrogen atoms, which may further have substituent(s);B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group;X is a divalent acyclic hydrocarbon group;Z is -O-, -S-, -NR2-, -CONR2- or -NR2CO- (R2 is a hydrogen atom or an optionally substituted alkyl group);Y is a bond or a divalent acyclic hydrocarbon group;R1 is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, provided that when the 5-membered aromatic heterocycle represented by ring A is imidazole, then Z should not be -O-, or a salt thereof.</p>
申请公布号 MXPA05004505(A) 申请公布日期 2005.07.26
申请号 MX2005PA04505 申请日期 2003.10.30
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 MISAYO SERA
分类号 A61K31/402;A61K31/415;A61K31/4155;A61K31/416;A61K31/4174;A61K31/4178;A61K31/4184;A61K31/427;A61K31/4439;A61K31/66;C07D231/12;C07D401/12;C07D403/12;C07D413/12;C07D417/12;C07F9/40;C07F9/553;C07F9/6503;C07F9/6506;C07F9/6518;C07F9/653;C07F9/6539;C07F9/6558;C07F9/6571;(IPC1-7):A61K31/381;A61K31/417;A61K31/418;A61K31/443;A61K31/537;C07D403/10;C07D417/04;C07D417/10 主分类号 A61K31/402
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