| 摘要 |
New benzimidazole derivatives of formula: <CHEM> in which R1 is H or a short chain hydrocarbon group such as methyl, ethyl, isopropyl, cyclopropyl, vinyl, etc., and R2 is a group selected from among the following: CH2OH, COOH, COOR3 and 4,4-dimethyl-2-oxazolinyl, R3 being a short chain alkyl group such as methyls ethyl, etc., are described. A description is also made of the preparation of these compounds, which have a high H1 antihistaminic and antiallergic activity and are devoid of effects on the central nervous and cardiovascuiar systems.
|
